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Cryo‐EM structure of the full‐length Lon protease from Thermus thermophilus
In bacteria, Lon is a large hexameric ATP‐dependent protease that targets misfolded and also folded substrates, some of which are involved in cell division and survival of cellular stress. The N‐terminal domain of Lon facilitates substrate recognition, but how the domains confer such activity has re...
Autores principales: | Coscia, Francesca, Löwe, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835725/ https://www.ncbi.nlm.nih.gov/pubmed/34591981 http://dx.doi.org/10.1002/1873-3468.14199 |
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