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Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury

Hemolysis is known to cause acute kidney injury (AKI). The iron regulatory hormone hepcidin, produced by renal distal tubules, is suggested to exert a renoprotective role during this pathology. We aimed to elucidate the molecular mechanisms of renal hepcidin synthesis and its protection against hemo...

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Detalles Bibliográficos
Autores principales: Diepeveen, Laura E., Stegemann, Gaby, Wiegerinck, Erwin T., Roelofs, Rian, Naber, Myrthe, Lóreal, Olivier, Smeets, Bart, Thévenod, Frank, Swinkels, Dorine W., van Swelm, Rachel P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835743/
https://www.ncbi.nlm.nih.gov/pubmed/35163276
http://dx.doi.org/10.3390/ijms23031352