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Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury
Hemolysis is known to cause acute kidney injury (AKI). The iron regulatory hormone hepcidin, produced by renal distal tubules, is suggested to exert a renoprotective role during this pathology. We aimed to elucidate the molecular mechanisms of renal hepcidin synthesis and its protection against hemo...
Autores principales: | Diepeveen, Laura E., Stegemann, Gaby, Wiegerinck, Erwin T., Roelofs, Rian, Naber, Myrthe, Lóreal, Olivier, Smeets, Bart, Thévenod, Frank, Swinkels, Dorine W., van Swelm, Rachel P. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835743/ https://www.ncbi.nlm.nih.gov/pubmed/35163276 http://dx.doi.org/10.3390/ijms23031352 |
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