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The Cumulative Formation of R-loop Interacts with Histone Modifications to Shape Cell Reprogramming

R-loop, a three-stranded RNA/DNA structure, plays important roles in modulating genome stability and gene expression, but the molecular mechanism of R-loops in cell reprogramming remains elusive. Here, we comprehensively profiled the genome-wide landscape of R-loops during cell reprogramming. The re...

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Detalles Bibliográficos
Autores principales: Li, Hanshuang, Long, Chunshen, Hong, Yan, Chao, Lemuge, Peng, Yong, Zuo, Yongchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835745/
https://www.ncbi.nlm.nih.gov/pubmed/35163490
http://dx.doi.org/10.3390/ijms23031567