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Challenges in Discovering Drugs That Target the Protein–Protein Interactions of Disordered Proteins

Protein–protein interactions (PPIs) outnumber proteins and are crucial to many fundamental processes; in consequence, PPIs are associated with several pathological conditions including neurodegeneration and modulating them by drugs constitutes a potentially major class of therapy. Classically, howev...

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Detalles Bibliográficos
Autores principales: Oláh, Judit, Szénási, Tibor, Lehotzky, Attila, Norris, Victor, Ovádi, Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835748/
https://www.ncbi.nlm.nih.gov/pubmed/35163473
http://dx.doi.org/10.3390/ijms23031550