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Challenges in Discovering Drugs That Target the Protein–Protein Interactions of Disordered Proteins
Protein–protein interactions (PPIs) outnumber proteins and are crucial to many fundamental processes; in consequence, PPIs are associated with several pathological conditions including neurodegeneration and modulating them by drugs constitutes a potentially major class of therapy. Classically, howev...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835748/ https://www.ncbi.nlm.nih.gov/pubmed/35163473 http://dx.doi.org/10.3390/ijms23031550 |