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The CAR–mRNA Interaction Surface Is a Zipper Extension of the Ribosome A Site

The ribosome CAR interaction surface behaves as an extension of the decoding center A site and has H-bond interactions with the +1 codon, which is next in line to enter the A site. Through molecular dynamic simulations, we investigated the codon sequence specificity of this CAR–mRNA interaction and...

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Detalles Bibliográficos
Autores principales: Dalgarno, Carol, Scopino, Kristen, Raval, Mitsu, Nachmanoff, Clara, Sakkas, Eric D., Krizanc, Daniel, Thayer, Kelly M., Weir, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835751/
https://www.ncbi.nlm.nih.gov/pubmed/35163343
http://dx.doi.org/10.3390/ijms23031417