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The CAR–mRNA Interaction Surface Is a Zipper Extension of the Ribosome A Site
The ribosome CAR interaction surface behaves as an extension of the decoding center A site and has H-bond interactions with the +1 codon, which is next in line to enter the A site. Through molecular dynamic simulations, we investigated the codon sequence specificity of this CAR–mRNA interaction and...
Autores principales: | Dalgarno, Carol, Scopino, Kristen, Raval, Mitsu, Nachmanoff, Clara, Sakkas, Eric D., Krizanc, Daniel, Thayer, Kelly M., Weir, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835751/ https://www.ncbi.nlm.nih.gov/pubmed/35163343 http://dx.doi.org/10.3390/ijms23031417 |
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