Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 Melanoma Cells Correlates with the Downregulation of Specific Onco-Proteins

Onconase (ONC) is an amphibian secretory ribonuclease displaying cytostatic and cytotoxic activities against many mammalian tumors, including melanoma. ONC principally damages tRNA species, but also other non-coding RNAs, although its precise targets are not known. We investigated the ONC ability to...

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Detalles Bibliográficos
Autores principales: De Tomi, Elisa, Campagnari, Rachele, Orlandi, Elisa, Cardile, Alessia, Zanrè, Valentina, Menegazzi, Marta, Gomez-Lira, Macarena, Gotte, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835754/
https://www.ncbi.nlm.nih.gov/pubmed/35163570
http://dx.doi.org/10.3390/ijms23031647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835754/
https://www.ncbi.nlm.nih.gov/pubmed/35163570
http://dx.doi.org/10.3390/ijms23031647

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