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Spheroid Culture Differentially Affects Cancer Cell Sensitivity to Drugs in Melanoma and RCC Models

2D culture as a model for drug testing often turns to be clinically futile. Therefore, 3D cultures (3Ds) show potential to better model responses to drugs observed in vivo. In preliminary studies, using melanoma (B16F10) and renal (RenCa) cancer, we confirmed that 3Ds better mimics the tumor microen...

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Detalles Bibliográficos
Autores principales: Filipiak-Duliban, Aleksandra, Brodaczewska, Klaudia, Kajdasz, Arkadiusz, Kieda, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835769/
https://www.ncbi.nlm.nih.gov/pubmed/35163092
http://dx.doi.org/10.3390/ijms23031166