In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators

Understanding the mechanisms of modulators’ action on enzymes is crucial for optimizing and designing pharmaceutical substances. The acute inflammatory response, in particular, is regulated mainly by a disintegrin and metalloproteinase (ADAM) 17. ADAM17 processes several disease mediators such as TN...

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Detalles Bibliográficos
Autores principales: Bienstein, Marian, Minond, Dmitriy, Schwaneberg, Ulrich, Davari, Mehdi D., Yildiz, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835787/
https://www.ncbi.nlm.nih.gov/pubmed/35163294
http://dx.doi.org/10.3390/ijms23031368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835787/
https://www.ncbi.nlm.nih.gov/pubmed/35163294
http://dx.doi.org/10.3390/ijms23031368

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