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In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators
Understanding the mechanisms of modulators’ action on enzymes is crucial for optimizing and designing pharmaceutical substances. The acute inflammatory response, in particular, is regulated mainly by a disintegrin and metalloproteinase (ADAM) 17. ADAM17 processes several disease mediators such as TN...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835787/ https://www.ncbi.nlm.nih.gov/pubmed/35163294 http://dx.doi.org/10.3390/ijms23031368 |