The K(+)-Dependent and -Independent Pyruvate Kinases Acquire the Active Conformation by Different Mechanisms

Eukarya pyruvate kinases possess glutamate at position 117 (numbering of rabbit muscle enzyme), whereas bacteria have either glutamate or lysine. Those with E117 are K(+)-dependent, whereas those with K117 are K(+)-independent. In a phylogenetic tree, 80% of the sequences with E117 are occupied by T...

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Detalles Bibliográficos
Autores principales: Ramírez-Silva, Leticia, Hernández-Alcántara, Gloria, Guerrero-Mendiola, Carlos, González-Andrade, Martin, Rodríguez-Romero, Adela, Rodríguez-Hernández, Annia, Lugo-Munguía, Alan, Gómez-Coronado, Paul A., Rodríguez-Méndez, Cristina, Vega-Segura, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835810/
https://www.ncbi.nlm.nih.gov/pubmed/35163274
http://dx.doi.org/10.3390/ijms23031347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835810/
https://www.ncbi.nlm.nih.gov/pubmed/35163274
http://dx.doi.org/10.3390/ijms23031347

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