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Indomethacin and Diclofenac Hybrids with Oleanolic Acid Oximes Modulate Key Signaling Pathways in Pancreatic Cancer Cells

Our earlier studies showed that coupling nonsteroidal anti-inflammatory drugs (NSAIDs) with oleanolic acid derivatives increased their anti-inflammatory activity in human hepatoma cells. The aim of this study was to evaluate their effect on the signaling pathways involved in inflammation processes i...

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Detalles Bibliográficos
Autores principales: Narożna, Maria, Krajka-Kuźniak, Violetta, Kleszcz, Robert, Baer-Dubowska, Wanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835846/
https://www.ncbi.nlm.nih.gov/pubmed/35163154
http://dx.doi.org/10.3390/ijms23031230