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Triptolide Suppresses NF-κB-Mediated Inflammatory Responses and Activates Expression of Nrf2-Mediated Antioxidant Genes to Alleviate Caerulein-Induced Acute Pancreatitis

Triptolide (TP), the main active ingredient of Tripterygium wilfordii Hook.f., displays potent anti-inflammatory, antioxidant, and antiproliferative activities. In the present study, the effect of TP on acute pancreatitis and the underlying mechanisms of the disease were investigated using a caerule...

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Detalles Bibliográficos
Autores principales: Yang, Jing, Tang, Xujiao, Ke, Xue, Dai, Yutong, Shi, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835869/
https://www.ncbi.nlm.nih.gov/pubmed/35163177
http://dx.doi.org/10.3390/ijms23031252