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Antibody Conjugated PLGA Nanocarriers and Superparmagnetic Nanoparticles for Targeted Delivery of Oxaliplatin to Cells from Colorectal Carcinoma

Anti-CD133 monoclonal antibody (Ab)-conjugated poly(lactide-co-glycolide) (PLGA) nanocarriers, for the targeted delivery of oxaliplatin (OXA) and superparamagnetic nanoparticles (IO-OA) to colorectal cancer cells (CaCo-2), were designed, synthesized, characterized, and evaluated in this study. The c...

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Detalles Bibliográficos
Autores principales: Zumaya, Alma Lucia Villela, Rimpelová, Silvie, Štějdířová, Markéta, Ulbrich, Pavel, Vilčáková, Jarmila, Hassouna, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835878/
https://www.ncbi.nlm.nih.gov/pubmed/35163122
http://dx.doi.org/10.3390/ijms23031200