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The Effect of Sodium-Dependent Glucose Cotransporter 2 Inhibitor Tofogliflozin on Neurovascular Coupling in the Retina in Type 2 Diabetic Mice

We investigated the effect of tofogliflozin, a sodium-dependent glucose cotransporter 2 inhibitor (SGLT2i), on retinal blood flow dysregulation, neural retinal dysfunction, and the impaired neurovascular coupling in type 2 diabetic mice. Tofogliflozin was added to mouse chow to deliver 5 mg/kg/day a...

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Detalles Bibliográficos
Autores principales: Hanaguri, Junya, Yokota, Harumasa, Kushiyama, Akifumi, Kushiyama, Sakura, Watanabe, Masahisa, Yamagami, Satoru, Nagaoka, Taiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835894/
https://www.ncbi.nlm.nih.gov/pubmed/35163285
http://dx.doi.org/10.3390/ijms23031362