Therapeutic Targets for DOX-Induced Cardiomyopathy: Role of Apoptosis vs. Ferroptosis

Doxorubicin (DOX) is the most widely used anthracycline anticancer agent; however, its cardiotoxicity limits its clinical efficacy. Numerous studies have elucidated the mechanisms underlying DOX-induced cardiotoxicity, wherein apoptosis has been reported as the most common final step leading to card...

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Detalles Bibliográficos
Autores principales: Kitakata, Hiroki, Endo, Jin, Ikura, Hidehiko, Moriyama, Hidenori, Shirakawa, Kohsuke, Katsumata, Yoshinori, Sano, Motoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835899/
https://www.ncbi.nlm.nih.gov/pubmed/35163335
http://dx.doi.org/10.3390/ijms23031414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835899/
https://www.ncbi.nlm.nih.gov/pubmed/35163335
http://dx.doi.org/10.3390/ijms23031414

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