The Effects of αvβ3 Integrin Blockage in Breast Tumor and Endothelial Cells under Hypoxia In Vitro

Breast cancer is characterized by a hypoxic microenvironment inside the tumor mass, contributing to cell metastatic behavior. Hypoxia induces the expression of hypoxia-inducible factor (HIF-1α), a transcription factor for genes involved in angiogenesis and metastatic behavior, including the vascular...

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Detalles Bibliográficos
Autores principales: Casali, Bruna C., Gozzer, Larissa T., Baptista, Matheus P., Altei, Wanessa F., Selistre-de-Araújo, Heloisa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835904/
https://www.ncbi.nlm.nih.gov/pubmed/35163668
http://dx.doi.org/10.3390/ijms23031745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835904/
https://www.ncbi.nlm.nih.gov/pubmed/35163668
http://dx.doi.org/10.3390/ijms23031745

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