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The Effects of αvβ3 Integrin Blockage in Breast Tumor and Endothelial Cells under Hypoxia In Vitro
Breast cancer is characterized by a hypoxic microenvironment inside the tumor mass, contributing to cell metastatic behavior. Hypoxia induces the expression of hypoxia-inducible factor (HIF-1α), a transcription factor for genes involved in angiogenesis and metastatic behavior, including the vascular...
Autores principales: | Casali, Bruna C., Gozzer, Larissa T., Baptista, Matheus P., Altei, Wanessa F., Selistre-de-Araújo, Heloisa S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835904/ https://www.ncbi.nlm.nih.gov/pubmed/35163668 http://dx.doi.org/10.3390/ijms23031745 |
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