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BMP9-ID1 Signaling Activates HIF-1α and VEGFA Expression to Promote Tumor Angiogenesis in Hepatocellular Carcinoma

Since hepatocellular carcinoma (HCC) is a typical hypervascular malignant tumor with poor prognosis, targeting angiogenesis is an important therapeutic strategy for advanced HCC. Involvement of bone morphologic protein 9 (BMP9), a transforming growth factor-beta superfamily member, has recently been...

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Detalles Bibliográficos
Autores principales: Chen, Han, Nio, Kouki, Tang, Hong, Yamashita, Taro, Okada, Hikari, Li, Yingyi, Doan, Phuong Thi Bich, Li, Ru, Lv, Junyan, Sakai, Yoshio, Yamashita, Tatsuya, Mizukoshi, Eishiro, Honda, Masao, Kaneko, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835914/
https://www.ncbi.nlm.nih.gov/pubmed/35163396
http://dx.doi.org/10.3390/ijms23031475