Alpha-Lipoic Acid Inhibits Spontaneous Diabetes and Autoimmune Recurrence in Non-Obese Diabetic Mice by Enhancing Differentiation of Regulatory T Cells and Showed Potential for Use in Cell Therapies for the Treatment of Type 1 Diabetes

Type 1 diabetes (T1D) is caused by the destruction of β cells in pancreatic islets by autoimmune T cells. Islet transplantation has been established as an effective treatment for T1D. However, the survival of islet grafts is often disrupted by recurrent autoimmunity. Alpha-lipoic acid (ALA) has been...

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Detalles Bibliográficos
Autores principales: Huang, Shing-Hwa, Kuo, Shun-Li, Chen, Shyi-Jou, Lin, Jeng-Rong, Chen, Yuan-Wu, Hong, Zhi-Jie, Sytwu, Huey-Kang, Lin, Gu-Jiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835933/
https://www.ncbi.nlm.nih.gov/pubmed/35163121
http://dx.doi.org/10.3390/ijms23031169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835933/
https://www.ncbi.nlm.nih.gov/pubmed/35163121
http://dx.doi.org/10.3390/ijms23031169

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