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Alpha-Lipoic Acid Inhibits Spontaneous Diabetes and Autoimmune Recurrence in Non-Obese Diabetic Mice by Enhancing Differentiation of Regulatory T Cells and Showed Potential for Use in Cell Therapies for the Treatment of Type 1 Diabetes
Type 1 diabetes (T1D) is caused by the destruction of β cells in pancreatic islets by autoimmune T cells. Islet transplantation has been established as an effective treatment for T1D. However, the survival of islet grafts is often disrupted by recurrent autoimmunity. Alpha-lipoic acid (ALA) has been...
Autores principales: | Huang, Shing-Hwa, Kuo, Shun-Li, Chen, Shyi-Jou, Lin, Jeng-Rong, Chen, Yuan-Wu, Hong, Zhi-Jie, Sytwu, Huey-Kang, Lin, Gu-Jiun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835933/ https://www.ncbi.nlm.nih.gov/pubmed/35163121 http://dx.doi.org/10.3390/ijms23031169 |
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