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Reductions in Hydrogen Sulfide and Changes in Mitochondrial Quality Control Proteins Are Evident in the Early Phases of the Corneally Kindled Mouse Model of Epilepsy

Epilepsy is a heterogenous neurological disorder characterized by recurrent unprovoked seizures, mitochondrial stress, and neurodegeneration. Hydrogen sulfide (H(2)S) is a gasotransmitter that promotes mitochondrial function and biogenesis, elicits neuromodulation and neuroprotection, and may acutel...

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Detalles Bibliográficos
Autores principales: Cho, Christi, Zeigler, Maxwell, Mizuno, Stephanie, Morrison, Richard S., Totah, Rheem A., Barker-Haliski, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835945/
https://www.ncbi.nlm.nih.gov/pubmed/35163358
http://dx.doi.org/10.3390/ijms23031434