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Interaction between miR4749 and Human Serum Albumin as Revealed by Fluorescence, FRET, Atomic Force Spectroscopy and Computational Modelling

The interaction of Human Serum Albumin (HSA) with the microRNA, miR4749, was investigated by Atomic Force Spectrscopy (AFS), static and time-resolved fluorescence spectroscopy and by computational methods. The formation of a HSA/miR4749 complex with an affinity of about 10(4) M(−1) has been assessed...

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Detalles Bibliográficos
Autores principales: Botti, Valentina, Marrone, Silvia, Cannistraro, Salvatore, Bizzarri, Anna Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835948/
https://www.ncbi.nlm.nih.gov/pubmed/35163220
http://dx.doi.org/10.3390/ijms23031291