LCZ696 Protects against Diabetic Cardiomyopathy-Induced Myocardial Inflammation, ER Stress, and Apoptosis through Inhibiting AGEs/NF-κB and PERK/CHOP Signaling Pathways

The present study is designed to determine the effect of LCZ696 on DCM in rats and investigate the underlying mechanism involved. Diabetes was induced by feeding rats with a high-fat diet for six weeks following a single injection of STZ (30 mg/kg). Diabetic rats were divided into three groups (n =...

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Detalles Bibliográficos
Autores principales: Belali, Osamah M., Ahmed, Mohammed M., Mohany, Mohamed, Belali, Tarig M., Alotaibi, Meshal M., Al-Hoshani, Ali, Al-Rejaie, Salim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836005/
https://www.ncbi.nlm.nih.gov/pubmed/35163209
http://dx.doi.org/10.3390/ijms23031288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836005/
https://www.ncbi.nlm.nih.gov/pubmed/35163209
http://dx.doi.org/10.3390/ijms23031288

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