Evaluation of the Impact of Esterases and Lipases from the Circulatory System against Substrates of Different Lipophilicity

Esterases and lipases can process amphiphilic esters used as drugs and prodrugs and impact their pharmacokinetics and biodistribution. These hydrolases can also process ester components of drug delivery systems (DDSs), thus triggering DDSs destabilization with premature cargo release. In this study...

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Detalles Bibliográficos
Autores principales: Lam, Leslie, Ilies, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836011/
https://www.ncbi.nlm.nih.gov/pubmed/35163184
http://dx.doi.org/10.3390/ijms23031262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836011/
https://www.ncbi.nlm.nih.gov/pubmed/35163184
http://dx.doi.org/10.3390/ijms23031262

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