K143R Amino Acid Substitution in 14-α-Demethylase (Erg11p) Changes Plasma Membrane and Cell Wall Structure of Candida albicans

The opportunistic pathogen Candida albicans is responsible for life-threating infections in immunocompromised individuals. Azoles and polyenes are two of the most commonly used antifungals and target the ergosterol biosynthesis pathway or ergosterol itself. A limited number of clinically employed an...

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Detalles Bibliográficos
Autores principales: Derkacz, Daria, Bernat, Przemysław, Krasowska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836035/
https://www.ncbi.nlm.nih.gov/pubmed/35163552
http://dx.doi.org/10.3390/ijms23031631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836035/
https://www.ncbi.nlm.nih.gov/pubmed/35163552
http://dx.doi.org/10.3390/ijms23031631

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