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Exosomal miRNAs from Prostate Cancer Impair Osteoblast Function in Mice

Prostate cancer (PCa) is the most frequent malignancy in older men with a high propensity for bone metastases. Characteristically, PCa causes osteosclerotic lesions as a result of disrupted bone remodeling. Extracellular vesicles (EVs) participate in PCa progression by conditioning the pre-metastati...

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Detalles Bibliográficos
Autores principales: Furesi, Giulia, de Jesus Domingues, Antonio Miguel, Alexopoulou, Dimitra, Dahl, Andreas, Hackl, Matthias, Schmidt, Johannes R., Kalkhof, Stefan, Kurth, Thomas, Taipaleenmäki, Hanna, Conrad, Stefanie, Hofbauer, Christine, Rauner, Martina, Hofbauer, Lorenz C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836054/
https://www.ncbi.nlm.nih.gov/pubmed/35163219
http://dx.doi.org/10.3390/ijms23031285