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Exosomal miRNAs from Prostate Cancer Impair Osteoblast Function in Mice
Prostate cancer (PCa) is the most frequent malignancy in older men with a high propensity for bone metastases. Characteristically, PCa causes osteosclerotic lesions as a result of disrupted bone remodeling. Extracellular vesicles (EVs) participate in PCa progression by conditioning the pre-metastati...
Autores principales: | Furesi, Giulia, de Jesus Domingues, Antonio Miguel, Alexopoulou, Dimitra, Dahl, Andreas, Hackl, Matthias, Schmidt, Johannes R., Kalkhof, Stefan, Kurth, Thomas, Taipaleenmäki, Hanna, Conrad, Stefanie, Hofbauer, Christine, Rauner, Martina, Hofbauer, Lorenz C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836054/ https://www.ncbi.nlm.nih.gov/pubmed/35163219 http://dx.doi.org/10.3390/ijms23031285 |
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