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Therapeutic Targeting of DNA Damage Response in Cancer

DNA damage response (DDR) is critical to ensure genome stability, and defects in this signaling pathway are highly associated with carcinogenesis and tumor progression. Nevertheless, this also provides therapeutic opportunities, as cells with defective DDR signaling are directed to rely on compensat...

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Detalles Bibliográficos
Autores principales: Choi, Wonyoung, Lee, Eun Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836062/
https://www.ncbi.nlm.nih.gov/pubmed/35163621
http://dx.doi.org/10.3390/ijms23031701