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Galangin Reverses H(2)O(2)-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling

UV radiation and H(2)O(2) are the primary factors that cause skin aging. Both trigger oxidative stress and cellular aging. It has been reported that deacetylase silent information regulator 1 (SIRT1), a longevity gene, enhances activation of NF-E2-related factor-2 (Nrf2), as well as its downstream k...

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Detalles Bibliográficos
Autores principales: Lee, Jian-Jr, Ng, Shang-Chuan, Hsu, Jia-Yun, Liu, Hsun, Chen, Chih-Jung, Huang, Chih-Yang, Kuo, Wei-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836071/
https://www.ncbi.nlm.nih.gov/pubmed/35163314
http://dx.doi.org/10.3390/ijms23031387