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R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1

Maintenance of genome stability is crucial for cell survival and relies on accurate DNA replication. However, replication fork progression is under constant attack from different exogenous and endogenous factors that can give rise to replication stress, a source of genomic instability and a notable...

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Detalles Bibliográficos
Autores principales: Marabitti, Veronica, Valenzisi, Pasquale, Lillo, Giorgia, Malacaria, Eva, Palermo, Valentina, Pichierri, Pietro, Franchitto, Annapaola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836129/
https://www.ncbi.nlm.nih.gov/pubmed/35163467
http://dx.doi.org/10.3390/ijms23031547