Cargando…

Calycosin, a Common Dietary Isoflavonoid, Suppresses Melanogenesis through the Downregulation of PKA/CREB and p38 MAPK Signaling Pathways

Calycosin, a bioactive isoflavonoid isolated from root extracts of Astragalus membranaceus, has been reported to inhibit melanogenesis, the mechanism of which remains undefined. In this study, we interrogated the mechanistic basis by which calycosin inhibits melanin production in two model systems,...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Kun-Chang, Hseu, You-Cheng, Shih, Yu-Ching, Sivakumar, Govindan, Syu, Jyun-Ting, Chen, Guan-Lin, Lu, Meng-Tien, Chu, Po-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836186/
https://www.ncbi.nlm.nih.gov/pubmed/35163281
http://dx.doi.org/10.3390/ijms23031358