Cargando…

A Palette of Fluorescent Aβ42 Peptides Labelled at a Range of Surface-Exposed Sites

Fluorescence-based single molecule techniques provide important tools towards understanding the molecular mechanism of complex neurodegenerative diseases. This requires efficient covalent attachment of fluorophores. Here we create a series of cysteine mutants (S8C, Y10C, S26C, V40C, and A42C) of A [...

Descripción completa

Detalles Bibliográficos
Autores principales: Thacker, Dev, Bless, Mara, Barghouth, Mohammad, Zhang, Enming, Linse, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836192/
https://www.ncbi.nlm.nih.gov/pubmed/35163577
http://dx.doi.org/10.3390/ijms23031655