Hyperglycemia Induces Inflammatory Response of Human Macrophages to CD163-Mediated Scavenging of Hemoglobin-Haptoglobin Complexes

Hyperglycemia, a hallmark of diabetes, can induce inflammatory programming of macrophages. The macrophage scavenger receptor CD163 internalizes and degrades hemoglobin-haptoglobin (Hb-Hp) complexes built due to intravascular hemolysis. Clinical studies have demonstrated a correlation between impaire...

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Detalles Bibliográficos
Autores principales: Matuschik, Laura, Riabov, Vladimir, Schmuttermaier, Christina, Sevastyanova, Tatyana, Weiss, Christel, Klüter, Harald, Kzhyshkowska, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836198/
https://www.ncbi.nlm.nih.gov/pubmed/35163309
http://dx.doi.org/10.3390/ijms23031385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836198/
https://www.ncbi.nlm.nih.gov/pubmed/35163309
http://dx.doi.org/10.3390/ijms23031385

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