Inhibition of the Akt/PKB Kinase Increases Na(v)1.6-Mediated Currents and Neuronal Excitability in CA1 Hippocampal Pyramidal Neurons

In neurons, changes in Akt activity have been detected in response to the stimulation of transmembrane receptors. However, the mechanisms that lead to changes in neuronal function upon Akt inhibition are still poorly understood. In the present study, we interrogate how Akt inhibition could affect th...

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Detalles Bibliográficos
Autores principales: Marosi, Mate, Nenov, Miroslav N., Di Re, Jessica, Dvorak, Nolan M., Alshammari, Musaad, Laezza, Fernanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836202/
https://www.ncbi.nlm.nih.gov/pubmed/35163623
http://dx.doi.org/10.3390/ijms23031700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836202/
https://www.ncbi.nlm.nih.gov/pubmed/35163623
http://dx.doi.org/10.3390/ijms23031700

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