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Inhibition of the Akt/PKB Kinase Increases Na(v)1.6-Mediated Currents and Neuronal Excitability in CA1 Hippocampal Pyramidal Neurons
In neurons, changes in Akt activity have been detected in response to the stimulation of transmembrane receptors. However, the mechanisms that lead to changes in neuronal function upon Akt inhibition are still poorly understood. In the present study, we interrogate how Akt inhibition could affect th...
Autores principales: | Marosi, Mate, Nenov, Miroslav N., Di Re, Jessica, Dvorak, Nolan M., Alshammari, Musaad, Laezza, Fernanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836202/ https://www.ncbi.nlm.nih.gov/pubmed/35163623 http://dx.doi.org/10.3390/ijms23031700 |
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