Water-Soluble Products of Photooxidative Destruction of the Bisretinoid A2E Cause Proteins Modification in the Dark

Aging of the retina is accompanied by a sharp increase in the content of lipofuscin granules and bisretinoid A2E in the cells of the retinal pigment epithelium (RPE) of the human eye. It is known that A2E can have a toxic effect on RPE cells. However, the specific mechanisms of the toxic effect of A...

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Detalles Bibliográficos
Autores principales: Dontsov, Alexander, Yakovleva, Marina, Trofimova, Natalia, Sakina, Natalia, Gulin, Alexander, Aybush, Arseny, Gostev, Fedor, Vasin, Alexander, Feldman, Tatiana, Ostrovsky, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836230/
https://www.ncbi.nlm.nih.gov/pubmed/35163454
http://dx.doi.org/10.3390/ijms23031534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836230/
https://www.ncbi.nlm.nih.gov/pubmed/35163454
http://dx.doi.org/10.3390/ijms23031534

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