Cargando…

Water-Soluble Products of Photooxidative Destruction of the Bisretinoid A2E Cause Proteins Modification in the Dark

Aging of the retina is accompanied by a sharp increase in the content of lipofuscin granules and bisretinoid A2E in the cells of the retinal pigment epithelium (RPE) of the human eye. It is known that A2E can have a toxic effect on RPE cells. However, the specific mechanisms of the toxic effect of A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dontsov, Alexander, Yakovleva, Marina, Trofimova, Natalia, Sakina, Natalia, Gulin, Alexander, Aybush, Arseny, Gostev, Fedor, Vasin, Alexander, Feldman, Tatiana, Ostrovsky, Mikhail
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836230/ https://www.ncbi.nlm.nih.gov/pubmed/35163454 http://dx.doi.org/10.3390/ijms23031534

Ejemplares similares

Lipofuscin Granule Bisretinoid Oxidation in the Human Retinal Pigment Epithelium forms Cytotoxic Carbonyls
por: Yakovleva, Marina, et al.
Publicado: (2021)

Understanding the Mechanism of Light-Induced Age-Related Decrease in Melanin Concentration in Retinal Pigment Epithelium Cells
por: Dontsov, Alexander E., et al.
Publicado: (2023)

Lipofuscin-Mediated Photic Stress Induces a Dark Toxic Effect on ARPE-19 Cells
por: Feldman, Tatiana, et al.
Publicado: (2022)

Lipofuscins prepared by modification of photoreceptor cells via glycation or lipid peroxidation show the similar phototoxicity
por: Dontsov, Alexander, et al.
Publicado: (2016)

Antioxidative Properties of Melanins and Ommochromes from Black Soldier Fly Hermetia illucens
por: Ushakova, Nina, et al.
Publicado: (2019)

Photobleaching and Fluorescence Recovery of RPE Bisretinoids
por: Liu, Zhao, et al.
Publicado: (2015)

Dark-adaptation in the eyes of a lake and a sea population of opossum shrimp (Mysis relicta): retinoid isomer dynamics, rhodopsin regeneration, and recovery of light sensitivity
por: Feldman, Tatiana, et al.
Publicado: (2020)

A high fat diet fosters elevated bisretinoids
por: Kim, Hye Jin, et al.
Publicado: (2023)

Iron promotes oxidative cell death caused by bisretinoids of retina
por: Ueda, Keiko, et al.
Publicado: (2018)

Bisretinoid phospholipid and vitamin A aldehyde: shining a light
por: Kim, Hye Jin, et al.
Publicado: (2021)

Femtosecond Laser Spectroscopy of the Rhodopsin Photochromic Reaction: A Concept for Ultrafast Optical Molecular Switch Creation (Ultrafast Reversible Photoreaction of Rhodopsin)
por: Smitienko, Olga, et al.
Publicado: (2014)

Selective Photooxidation Reactions using Water‐Soluble Anthraquinone Photocatalysts
por: Zhang, Wuyuan, et al.
Publicado: (2017)

Photo-products of retinal pigment epithelial bisretinoids react with cellular thiols
por: Yoon, Kee Dong, et al.
Publicado: (2011)

Bisretinoids of the Retina: Photo-Oxidation, Iron-Catalyzed Oxidation, and Disease Consequences
por: Kim, Hye Jin, et al.
Publicado: (2021)

A vicious cycle of bisretinoid formation and oxidation relevant to recessive Stargardt disease
por: Zhao, Jin, et al.
Publicado: (2021)

Switching the Mechanism of NADH Photooxidation by Supramolecular Interactions
por: Mengele, Alexander K., et al.
Publicado: (2021)

PHOTOOXIDATIONS IN PIGMENTED BLEPHARISMA
por: Giese, Arthur C., et al.
Publicado: (1949)

Ultrafast Spectroscopy of Fano-Like Resonance between Optical Phonon and Excitons in CdSe Quantum Dots: Dependence of Coherent Vibrational Wave-Packet Dynamics on Pump Fluence
por: Nadtochenko, Victor, et al.
Publicado: (2017)

Bisretinoid degradation and reduction of lipofuscin accumulation in the amelanotic retinal pigment epithelium of mammals with a tapetum
por: Pfeffer, Bruce A.
Publicado: (2023)

Photooxidation of n-Hexanal in Air
por: Tadić, Jovan, et al.
Publicado: (2001)

Microwave-assisted photooxidation of sulfoxides
por: Matsukawa, Yuta, et al.
Publicado: (2021)

Photooxidative stress-inducible orange and pink water-soluble astaxanthin-binding proteins in eukaryotic microalga
por: Kawasaki, Shinji, et al.
Publicado: (2020)

Photooxidation crosslinking to recover residual stress in decellularized blood vessel
por: Wang, Jintao, et al.
Publicado: (2021)

PHOTOOXIDATION OF DIAMINOBENZIDINE (DAB) BY CHLOROPLAST LAMELLAE
por: Nir, Izhak, et al.
Publicado: (1970)

Hierarchical porous photosensitizers with efficient photooxidation
por: Fang, Yajun, et al.
Publicado: (2023)

Metabolic imaging and secondary ion mass spectrometry to define the structure and function of liver with acute and chronic pathology
por: Kuznetsova, Daria, et al.
Publicado: (2019)

Optical Properties of Secondary Organic Aerosol Produced by Photooxidation of Naphthalene under NOx Condition
por: He, Quanfu, et al.
Publicado: (2022)

Metal‐Catalyzed Photooxidation of Flavones in Aqueous Media
por: Abdolahzadeh, Shaghayegh, et al.
Publicado: (2018)

Photooxidation of Some Metallocenes in a Polymer Matrix
por: Mallik, Biswanath
Publicado: (2005)

Spectroscopic Evidence for Photooxidation of Tocopherols in n-Hexane
por: Smyk, Bogdan
Publicado: (2021)

FERONIA Confers Resistance to Photooxidative Stress in Arabidopsis
por: Shin, Seung Yong, et al.
Publicado: (2021)

A Self‐Assembling Flavin for Visible Photooxidation
por: Cariello, Michele, et al.
Publicado: (2022)

The photooxidative destruction of C.I. Basic Yellow 2 using UV/S(2)O(8)(2−) process in a rectangular continuous photoreactor
por: Salari, D., et al.
Publicado: (2009)

Lake and Sea Populations of Mysis relicta (Crustacea, Mysida) with Different Visual-Pigment Absorbance Spectra Use the Same A1 Chromophore
por: Belikov, Nikolai, et al.
Publicado: (2014)

Chemical and Light-Absorption Properties of Water-Soluble Organic Aerosols in Northern California and Photooxidant Production by Brown Carbon Components
por: Jiang, Wenqing, et al.
Publicado: (2023)

Retinal Pigment Epithelium in Human Donor Eyes Contains Higher Levels of Bisretinoids Including A2E in Periphery than Macula
por: Kotnala, Ankita, et al.
Publicado: (2022)

Photooxidation Tolerance Characters of a New Purple Pepper
por: Ou, Li-jun, et al.
Publicado: (2013)

Reactive species involved in the regioselective photooxidation of heptamethine cyanines
por: Nani, Roger R., et al.
Publicado: (2015)

Rapid conversion of isoprene photooxidation products in terrestrial plants
por: Canaval, Eva, et al.
Publicado: (2020)

Machine learning prediction of methionine and tryptophan photooxidation susceptibility
por: Delmar, Jared A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rkfiv8kq9lrn4ml2s39gr9vtt6