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Single-Cell Analysis Uncovers Osteoblast Factor Growth Differentiation Factor 10 as Mediator of Vascular Smooth Muscle Cell Phenotypic Modulation Associated with Plaque Rupture in Human Carotid Artery Disease

(1) Background: Vascular smooth muscle cells (VSMCs) undergo a complex phenotypic switch in response to atherosclerosis environmental triggers, contributing to atherosclerosis disease progression. However, the complex heterogeneity of VSMCs and how VSMC dedifferentiation affects human carotid artery...

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Detalles Bibliográficos
Autores principales: Brandt, Karim J., Burger, Fabienne, Baptista, Daniela, Roth, Aline, Fernandes da Silva, Rafaela, Montecucco, Fabrizio, Mach, Francois, Miteva, Kapka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836240/
https://www.ncbi.nlm.nih.gov/pubmed/35163719
http://dx.doi.org/10.3390/ijms23031796