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Gene Transfer of Skeletal Muscle-Type Myosin Light Chain Kinase via Adeno-Associated Virus 6 Improves Muscle Functions in an Amyotrophic Lateral Sclerosis Mouse Model

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that shows progressive muscle weakness. A few treatments exist including symptomatic therapies, which can prolong survival or reduce a symptom; however, no fundamental therapies have been found. As a therapeutic strategy, enhancing m...

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Detalles Bibliográficos
Autores principales: Oya, Ryohei, Tsukamoto, Osamu, Hitsumoto, Tatsuro, Nakahara, Naoya, Okamoto, Chisato, Matsuoka, Ken, Kato, Hisakazu, Inohara, Hidenori, Takashima, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836241/
https://www.ncbi.nlm.nih.gov/pubmed/35163674
http://dx.doi.org/10.3390/ijms23031747