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Gene Transfer of Skeletal Muscle-Type Myosin Light Chain Kinase via Adeno-Associated Virus 6 Improves Muscle Functions in an Amyotrophic Lateral Sclerosis Mouse Model
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that shows progressive muscle weakness. A few treatments exist including symptomatic therapies, which can prolong survival or reduce a symptom; however, no fundamental therapies have been found. As a therapeutic strategy, enhancing m...
Autores principales: | Oya, Ryohei, Tsukamoto, Osamu, Hitsumoto, Tatsuro, Nakahara, Naoya, Okamoto, Chisato, Matsuoka, Ken, Kato, Hisakazu, Inohara, Hidenori, Takashima, Seiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836241/ https://www.ncbi.nlm.nih.gov/pubmed/35163674 http://dx.doi.org/10.3390/ijms23031747 |
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