Identification of Potential Antiviral Inhibitors from Hydroxychloroquine and 1,2,4,5-Tetraoxanes Analogues and Investigation of the Mechanism of Action in SARS-CoV-2

This study aimed to identify potential inhibitors and investigate the mechanism of action on SARS-CoV-2 ACE2 receptors using a molecular modeling study and theoretical determination of biological activity. Hydroxychloroquine was used as a pivot structure and antimalarial analogues of 1,2,4,5 tetraox...

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Detalles Bibliográficos
Autores principales: Ramos, Ryan S., Borges, Rosivaldo S., de Souza, João S. N., Araujo, Inana F., Chaves, Mariana H., Santos, Cleydson B. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836247/
https://www.ncbi.nlm.nih.gov/pubmed/35163703
http://dx.doi.org/10.3390/ijms23031781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836247/
https://www.ncbi.nlm.nih.gov/pubmed/35163703
http://dx.doi.org/10.3390/ijms23031781

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