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Structural Basis of Redox-Sensing Transcriptional Repressor Rex with Cofactor NAD(+) and Operator DNA

The transcriptional repressor Rex plays important roles in regulating the expression of respiratory genes by sensing the reduction–oxidation (redox) state according to the intracellular NAD(+)/NADH balance. Previously, we reported on crystal structures of apo, NAD(+)-bound, and NADH-bound forms of R...

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Detalles Bibliográficos
Autores principales: Jeong, Kang Hwa, Lee, Hyun Jin, Park, Young Woo, Lee, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836258/
https://www.ncbi.nlm.nih.gov/pubmed/35163512
http://dx.doi.org/10.3390/ijms23031578