Oncogenic Mutation BRAF V600E Changes Phenotypic Behavior of THLE-2 Liver Cells through Alteration of Gene Expression

The accumulation of mutations in cancer driver genes, such as tumor suppressors or proto-oncogenes, affects cellular homeostasis. Disturbances in the mechanism controlling proliferation cause significant augmentation of cell growth and division due to the loss of sensitivity to the regulatory signal...

Descripción completa

Detalles Bibliográficos
Autores principales: Śmiech, Magdalena, Leszczyński, Paweł, Wardell, Christopher, Poznański, Piotr, Pierzchała, Mariusz, Taniguchi, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836259/
https://www.ncbi.nlm.nih.gov/pubmed/35163468
http://dx.doi.org/10.3390/ijms23031548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836259/
https://www.ncbi.nlm.nih.gov/pubmed/35163468
http://dx.doi.org/10.3390/ijms23031548

Ejemplares similares