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Involvement of Mitochondrial Mechanisms and Cyclooxygenase-2 Activation in the Effect of Desethylamiodarone on 4T1 Triple-Negative Breast Cancer Line

Novel compounds significantly interfering with the mitochondrial energy production may have therapeutic value in triple-negative breast cancer (TNBC). This criterion is clearly fulfilled by desethylamiodarone (DEA), which is a major metabolite of amiodarone, a widely used antiarrhythmic drug, since...

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Detalles Bibliográficos
Autores principales: Gallyas, Ferenc, Ramadan, Fadi H. J., Andreidesz, Kitti, Hocsak, Eniko, Szabo, Aliz, Tapodi, Antal, Kiss, Gyongyi N., Fekete, Katalin, Bognar, Rita, Szanto, Arpad, Bognar, Zita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836269/
https://www.ncbi.nlm.nih.gov/pubmed/35163464
http://dx.doi.org/10.3390/ijms23031544