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Effect of Ions and Sequence Variants on the Antagonist Binding Properties of the Histamine H(1) Receptor

The histamine H(1) receptor (H(1)R) is a G protein-coupled receptor (GPCR) and represents a main target in the treatment of allergic reactions as well as inflammatory reactions and depressions. Although the overall effect of antagonists on H(1) function has been extensively investigated, rather litt...

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Detalles Bibliográficos
Autores principales: Conrad, Marcus, Söldner, Christian A., Sticht, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836275/
https://www.ncbi.nlm.nih.gov/pubmed/35163341
http://dx.doi.org/10.3390/ijms23031420