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10-Dehydrogingerdione Attenuates Tramadol-Induced Nephrotoxicity by Modulating Renal Oxidative Stress, Inflammation and Apoptosis in Experimental Rats: Role of HO-1 Activation and TLR4/NF-κB/ERK Inhibition

Tramadol represents a synthetic opioid analgesic especially for mild to severe pain. Its dose must be commonly monitored according to pain status and to alleviate the appearance of any adverse effects such as renal cellular damage during its excretion. Present work aimed mainly to study the effects...

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Detalles Bibliográficos
Autores principales: Elnagar, Gehad M., Elseweidy, Mohamed M., Mahmoud, Yasmin K., Elkomy, Nesreen M. I. M., Althafar, Ziyad M., Alnomasy, Sultan F., Al-Gabri, Naif A., Shawky, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836278/
https://www.ncbi.nlm.nih.gov/pubmed/35163308
http://dx.doi.org/10.3390/ijms23031384