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10-Dehydrogingerdione Attenuates Tramadol-Induced Nephrotoxicity by Modulating Renal Oxidative Stress, Inflammation and Apoptosis in Experimental Rats: Role of HO-1 Activation and TLR4/NF-κB/ERK Inhibition
Tramadol represents a synthetic opioid analgesic especially for mild to severe pain. Its dose must be commonly monitored according to pain status and to alleviate the appearance of any adverse effects such as renal cellular damage during its excretion. Present work aimed mainly to study the effects...
Autores principales: | Elnagar, Gehad M., Elseweidy, Mohamed M., Mahmoud, Yasmin K., Elkomy, Nesreen M. I. M., Althafar, Ziyad M., Alnomasy, Sultan F., Al-Gabri, Naif A., Shawky, Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836278/ https://www.ncbi.nlm.nih.gov/pubmed/35163308 http://dx.doi.org/10.3390/ijms23031384 |
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