Essential role of pyrophosphate homeostasis mediated by the pyrophosphate-dependent phosphofructokinase in Toxoplasma gondii

Many biosynthetic pathways produce pyrophosphate (PPi) as a by-product, which is cytotoxic if accumulated at high levels. Pyrophosphatases play pivotal roles in PPi detoxification by converting PPi to inorganic phosphate. A number of apicomplexan parasites, including Toxoplasma gondii and Cryptospor...

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Detalles Bibliográficos
Autores principales: Yang, Xuke, Yin, Xiaoyan, Liu, Jiaojiao, Niu, Zhipeng, Yang, Jichao, Shen, Bang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836295/
https://www.ncbi.nlm.nih.gov/pubmed/35104280
http://dx.doi.org/10.1371/journal.ppat.1010293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836295/
https://www.ncbi.nlm.nih.gov/pubmed/35104280
http://dx.doi.org/10.1371/journal.ppat.1010293

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